The Cardiovascular Atlas

CVD Atlas

Reperfusion strategy in acute ST elevation acute myocardial infarction (STEMI)

Reperfusion therapy is recommended in all patients with a working diagnosis of STEMI (persistent ST-segment elevation or equivalents) and symptoms of ischaemia of ≤12 h duration. (I, A)

Primary PCI
For symptom duration of 0 hours to 12 hours:

  • PPCI is recommended if the time to wire passing is less than 120 minutes (class Ia).
  • PPCI is also recommended (class Ic) in unstable patients, including those with recurrent ventricular arrhythmias.

For symptom duration of 12 hours to 48 hours:

  • PPCI should be considered (class IIa), irrespective of symptoms.

Fibrinolysis: Fibrinolysis is recommended if the time to wire passing is greater than 120 minutes (class Ia) and symptom duration is <12 hours.

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