
Reperfusion therapy is recommended in all patients with a working diagnosis of STEMI (persistent ST-segment elevation or equivalents) and symptoms of ischaemia of ≤12 h duration. (I, A)
Primary PCI
For symptom duration of 0 hours to 12 hours:
- PPCI is recommended if the time to wire passing is less than 120 minutes (class Ia).
- PPCI is also recommended (class Ic) in unstable patients, including those with recurrent ventricular arrhythmias.
For symptom duration of 12 hours to 48 hours:
- PPCI should be considered (class IIa), irrespective of symptoms.
Fibrinolysis: Fibrinolysis is recommended if the time to wire passing is greater than 120 minutes (class Ia) and symptom duration is <12 hours.