Tools and Manuals for Cardiovascular Medicine

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Reference Values for Adult Echocardiography

Normal Values for Two-Dimensional Echocardiographic Parameters of Left Ventricular Size and Function According to Sex

ParameterMale Mean ± SDMale 2-SD RangeFemale Mean ± SDFemale 2-SD Range
Left Ventricular (LV) Internal Dimension
Diastolic dimension50.2 ± 4.142.0–58.445.0 ± 3.637.8–52.2
Systolic dimension32.4 ± 3.725.0–39.828.2 ± 3.121.6–34.8
LV Volumes (Biplane)
LV EDV (mL)106 ± 2262–15076 ± 1546–106
LV ESV (mL)41 ± 1021–6128 ± 714–42
LV Volumes Normalized by Body Surface Area
LV EDV (mL/m²)54 ± 1034–7445 ± 829–61
LV ESV (mL/m²)21 ± 511–3116 ± 48–24
LV EF (biplane)62 ± 552–7261 ± 454–74
EDV, End-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; SD, standard deviation.

Normal Ranges for Left Ventricular (LV) Mass Indices

IndexWomenMen
Linear Method
LV mass (g)67–16288–224
LV mass/BSA (g/m²)43–9549–115
Relative wall thickness (cm)0.22–0.420.24–0.42
Septal thickness (cm)0.6–0.90.6–1.0
Posterior wall thickness (cm)0.6–0.90.6–1.0
Two-Dimensional Method
LV mass (g)66–15096–200
LV mass/BSA (g/m²)44–8850–102
Bold/italic values: Recommended and best validated.

Normal Ranges and Severity Partition Cutoff Values for Two-Dimensional Echocardiography-Derived Left Ventricular Ejection Fraction (LVEF) and Left Atrial (LA) Volume

Male Normal RangeMale Mildly AbnormalMale Moderately AbnormalMale Severely AbnormalFemale Normal RangeFemale Mildly AbnormalFemale Moderately AbnormalFemale Severely Abnormal
LVEF (%)52–7241–5130–40<3054–7441–5330–40<30
Max LA vol/BSA (mL/m²)16–3435–4142–48>4816–3435–4142–48>48

Left Ventricular (LV) Relaxation, Filling Pressures, and Two-Dimensional and Doppler Findings According to LV Diastolic Function

ParameterNormalGrade IGrade IIGrade III
LV relaxationNormalImpairedImpairedImpaired
LA pressureNormalLow or normalElevatedElevated
Mitral E/A ratio≥0.8<0.8>0.8 to <2>2
Average E/e’ ratio<10<1010–14>14
Peak TR velocity (m/sec)<2.8<2.8>2.8>2.8
LA volume indexNormalNormal or increased (>34 ml/m²)IncreasedIncreased
LA, Left atrial; TR, tricuspid regurgitation. From Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016;29:277.

Normal Values for Right Ventricular (RV) Chamber Size

ParameterMean ± SDNormal Range
RV basal diameter (mm)33 ± 425–41
RV mid diameter (mm)27 ± 319–35
RV longitudinal diameter (mm)71 ± 659–83
RVOT PLAX diameter (mm)25 ± 2.520–30
RVOT proximal diameter (mm)28 ± 3.521–35
RVOT distal diameter (mm)22 ± 1.717–27
RV wall thickness (mm)3 ± 11–5
RVOT EDA (cm²)
Men17 ± 3.510–24
Women14 ± 38–20
RV EDA indexed to BSA (cm²/m²)
Men8.8 ± 1.95–12.6
Women8.0 ± 1.754.5–11.5
RV ESA (cm²)
Men9 ± 33–15
Women7 ± 23–11
RV ESA indexed to BSA (cm²/m²)
Men4.7 ± 1.352.0–7.4
Women4.0 ± 1.21.6–6.4
RV SEDV indexed to BSA (mL/m²)
Men61 ± 1335–87
Women53 ± 10.532–74
RV ESV indexed to BSA (mL/m²)
Men27 ± 8.510–44
Women22 ± 78–36
BSA, Body surface area; EDA, end-diastolic area; ESA, end-systolic area; PLAX, parasternal long-axis view; RVOT, RV outflow tract. From Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28:1.

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