Figure 1. Chest pain is the hallmark of myocardial ischemia. It signals that there is ongoing (acute) myocardial ischemia. Careful assessment of the symptoms is crucial to promptly establish a working diagnosis. Chest pain due to myocardial ischemia is rather characteristic, which means that the vast majority of patients with acute coronary syndromes can be treated before troponin test results have arrived. Hence, assessment of symptoms and ECG is sufficient to manage patients with chest pain.