The Cardiovascular
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Vancouver Chest Pain Rule

2-hour rule-out for early discharge of low-risk emergency department chest pain.

Vancouver Chest Pain Rule
Ischemic ECG changes (new, not known to be old)
Initial (0h) troponin above the 99th percentile
2-hour troponin above the 99th percentile
Chest pain fully reproducible by palpation
Age <40 years
Known coronary artery disease (prior MI, PCI, CABG, or angina)
Pain radiates to neck, jaw, or either arm
Diaphoresis witnessed with this episode
Pain is part of an accelerating/worsening pattern
ResultNot low risk

Does not satisfy either low-risk pathway; consider further risk stratification.

When to use

  • Deciding whether a patient with possible ischemic chest pain can be safely discharged after 2 hours of ED evaluation without further provocative testing.

Formula

Decision rule (not a summed score): safe for early discharge if either (a) age <40, no known CAD, no typical radiation, no diaphoresis, non-worsening pattern, plus a normal ECG and negative 0h/2h troponin, or (b) chest pain fully reproducible by palpation plus a normal ECG and negative 0h/2h troponin.

Pearls and pitfalls

  • Designed to identify a low-risk subgroup safe for outpatient follow-up, not to rule in ACS.
  • Any ischemic ECG change or troponin elevation overrides both low-risk pathways.

References

  1. Christenson J, Innes G, McKnight D, et al. Ann Emerg Med. 2006;47(1):1-10.