The Cardiovascular
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Shanghai Score for Brugada Syndrome

Shanghai Score for Brugada Syndrome
ECG findings (highest applicable)
Clinical history (highest applicable)
Family history (highest applicable)
Probable pathogenic mutation in a Brugada-susceptibility gene
Result0.0 points

Non-diagnostic

Diagnostic category
Non-diagnostic

When to use

  • Structuring the diagnostic work-up of suspected Brugada syndrome by combining ECG pattern, personal and family history, and genetic testing.

Formula

Sum of the single highest-scoring item in each of 3 categories (ECG, clinical history, family history) plus 0.5 if a pathogenic mutation is identified. <2 = non-diagnostic, 2-3 = possible, ≥3.5 = probable/definite.

Pearls and pitfalls

  • ECG findings must be interpreted in the absence of confounders (fever, ischemia, electrolyte disturbance, etc.) that can mimic a type 1 pattern.

References

  1. Antzelevitch C, et al. Heart Rhythm. 2016;13(10):e295-e324.