The Cardiovascular
ToolsCalculators

Shanghai Score for Brugada Syndrome

Multiparametric diagnostic score combining ECG, history, family history, and genetics.

Shanghai Score for Brugada Syndrome
ECG findings (highest applicable)
Clinical history (highest applicable)
Family history (highest applicable)
Probable pathogenic mutation in a Brugada-susceptibility gene
Result0.0 points

Non-diagnostic

Diagnostic category
Non-diagnostic

When to use

  • Structuring the diagnostic work-up of suspected Brugada syndrome by combining ECG pattern, personal and family history, and genetic testing.

Formula

Sum of the single highest-scoring item in each of 3 categories (ECG, clinical history, family history) plus 0.5 if a pathogenic mutation is identified. <2 = non-diagnostic, 2-3 = possible, ≥3.5 = probable/definite.

Pearls and pitfalls

  • ECG findings must be interpreted in the absence of confounders (fever, ischemia, electrolyte disturbance, etc.) that can mimic a type 1 pattern.

References

  1. Antzelevitch C, et al. Heart Rhythm. 2016;13(10):e295-e324.