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Rome IV Diagnostic Criteria for Child Functional Nausea and Vomiting

Diagnostic checklist for functional nausea and functional vomiting in children.

Rome IV Diagnostic Criteria for Child Functional Nausea and Vomiting
Bothersome nausea as the predominant symptom, ≥2 times per week, generally not related to meals
Nausea not consistently associated with vomiting
Nausea not fully explained by another medical condition after appropriate evaluation
≥1 episode of vomiting per week, on average
No self-induced vomiting and criteria for an eating disorder or rumination syndrome are not met
Vomiting not fully explained by another medical condition after appropriate evaluation
Criteria fulfilled for at least 2 months prior to diagnosis
ResultCriteria not met

Neither the functional nausea nor the functional vomiting criteria are fulfilled as entered.

Functional nausea criteria
Not met
Functional vomiting criteria
Not met

When to use

  • Evaluating a child with chronic nausea and/or vomiting once an organic cause has been excluded.

Formula

Functional nausea: bothersome nausea ≥2x/week, generally not meal-related, not consistently associated with vomiting, unexplained by another medical condition, for ≥2 months. Functional vomiting: ≥1 vomiting episode/week on average, no self-induced vomiting, eating disorder, or rumination, unexplained by another medical condition, for ≥2 months.

References

  1. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Functional Disorders: Children and Adolescents. Gastroenterology. 2016;150(6):1456-1468.