ToolsCalculators
Plasma Dosage
Estimated fresh frozen plasma volume to raise coagulation factor activity by a desired percentage.
Plasma Dosage
Body weight
Hematocrit
%
Desired increase in factor activity
%
Complete the fields above to see the result.
When to use
- Estimating an FFP dose to correct a specific coagulation factor deficit before an invasive procedure or for active bleeding.
Formula
Plasma volume (mL) = weight (kg) x 70 mL/kg x (1 - hematocrit/100). FFP dose (mL) = plasma volume x (desired % increase in factor activity / 100).
Pearls and pitfalls
- Most factors recover at roughly 1 mL FFP/kg raising activity by about 1-2%; 10-15 mL/kg is a typical empiric starting dose.