The Cardiovascular
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Pediatric Crohn's Disease Activity Index (PCDAI)

Grades disease activity in children and adolescents with Crohn's disease.

Pediatric Crohn's Disease Activity Index (PCDAI)
Abdominal pain (past week)
Stools (past week)
General well-being (past week)
Usual (baseline) weight
Current weight
Height velocity (growth chart)
Abdominal exam
Perirectal disease
Extraintestinal manifestations (fever >=38.5C x3 days, arthritis, uveitis, erythema nodosum, pyoderma gangrenosum)
Age
years
Sex
Hematocrit
%
ESR
mm/hr
Albumin
Complete the fields above to see the result.

When to use

  • Grading disease activity and monitoring treatment response in children and adolescents with known Crohn's disease.

Formula

Weighted sum of symptom, exam, growth, and laboratory items (weight loss %, age/sex-specific hematocrit, ESR, albumin). Range 0-100. <=10 remission, 11-30 mild, >30 moderate-to-severe.

Pearls and pitfalls

  • Weight, hematocrit, and ESR items require a recent baseline for comparison — apparent stability can mask early relapse.
  • A revised (weighted) PCDAI exists but this reproduces the original 1991 index.

References

  1. Hyams JS, Ferry GD, Mandel FS, et al. J Pediatr Gastroenterol Nutr. 1991;12(4):439-47.