ToolsCalculators
Metabolic Score for Insulin Resistance (METS-IR)
Non-insulin surrogate index of insulin resistance and future type 2 diabetes risk from routine labs and BMI.
Metabolic Score for Insulin Resistance (METS-IR)
Fasting glucose
Fasting triglycerides
HDL cholesterol
Weight
Height
Complete the fields above to see the result.
When to use
- Estimating insulin resistance and future type 2 diabetes risk from a routine metabolic panel and anthropometrics, without requiring an insulin level.
Formula
METS-IR = Ln[(2 x fasting glucose [mg/dL]) + triglycerides [mg/dL]] x BMI [kg/m2] / Ln[HDL-C [mg/dL]].
Pearls and pitfalls
- Correlates well with the hyperinsulinemic-euglycemic clamp and HOMA-IR without needing an insulin assay.
- Cut-points for insulin resistance vary by population; use cohort-specific thresholds where available rather than a single universal cutoff.