ToolsCalculators
Intrauterine RBC transfusion dosage
Donor red-cell volume for fetal intravascular transfusion.
Intrauterine RBC transfusion dosage
Estimated fetal weight
g
Fetal hematocrit (pre-transfusion)
%
Desired fetal hematocrit
%
Complete the fields above to see the result.
When to use
- Estimating the donor packed-RBC volume for ultrasound-guided intrauterine intravascular transfusion of an anemic fetus (e.g., red-cell alloimmunization, parvovirus B19).
Formula
Transfusion volume (mL) = transfusion coefficient (0.02) x estimated fetal weight (g) x [(desired Hct - initial fetal Hct) / 10].
Pearls and pitfalls
- The 0.02 mL/g coefficient was derived empirically and performed comparably to Mandelbrot's method and better than Plecas' method in the original validation.
- Treat this as a pre-procedure estimate; the actual volume infused should be guided by real-time intraoperative hematocrit sampling.