ToolsCalculators
Hypothermia Outcome Prediction after ECLS (HOPE) Score
Predicts probability of survival after extracorporeal life support rewarming for hypothermic cardiac arrest.
Hypothermia Outcome Prediction after ECLS (HOPE) Score
Sex
Age
years
Mechanism of hypothermia
Core temperature at admission
°C
Serum potassium at admission
mmol/L
Duration of CPR before ECLS
minutes
Complete the fields above to see the result.
When to use
- Estimating survival probability before or during rewarming with extracorporeal life support for accidental hypothermic cardiac arrest.
- Supplementing a serum potassium-only triage approach with additional admission variables.
Formula
Logit = 2.44 − 1.55×male − 1.95×asphyxia-related mechanism − 0.0191×age − 2.07×log2(potassium in mmol/L) − 0.573×log2(CPR duration in minutes) + 0.937×core temperature (°C) − 0.0247×core temperature². Predicted survival probability = e^logit / (1 + e^logit).
Pearls and pitfalls
- Outperformed triage based on serum potassium alone in the derivation cohort (AUC 0.90 vs 0.77).
- Developed from patients who already underwent ECLS rewarming; use cautiously as the sole determinant of candidacy.