ToolsCalculators
HOMA-IR (insulin resistance)
Estimates insulin resistance from fasting glucose and insulin.
HOMA-IR (insulin resistance)
Fasting insulin
uU/mL
Fasting glucose
Complete the fields above to see the result.
When to use
- Screening for or quantifying insulin resistance in non-diabetic or research settings.
Formula
HOMA-IR = (fasting insulin [uU/mL] x fasting glucose [mg/dL]) / 405. With glucose in mmol/L, divide by 22.5 instead.
Pearls and pitfalls
- Requires a true fasting sample; unreliable once endogenous insulin secretion fails (advanced type 2 or type 1 diabetes).
- Cut-offs are population- and assay-specific rather than universal.