The Cardiovascular
ToolsCalculators

HCM Risk-SCD

5-year risk of sudden cardiac death in hypertrophic cardiomyopathy.

HCM Risk-SCD
Age at evaluation
years
Maximal left-ventricular wall thickness
mm
Left atrial diameter
mm
Maximal LVOT gradient (rest/Valsalva)
mmHg
Family history of sudden cardiac death
Non-sustained ventricular tachycardia on ambulatory monitoring
Unexplained syncope
Complete the fields above to see the result.

When to use

  • Estimating the need for a primary-prevention implantable cardioverter-defibrillator in patients with hypertrophic cardiomyopathy.

Formula

Prognostic index = 0.15939858 x MWT - 0.00294271 x MWT^2 + 0.0259082 x LA diameter + 0.00446131 x max LVOT gradient + 0.4583082 x family history SCD + 0.82639195 x NSVT + 0.71650361 x unexplained syncope - 0.01799934 x age. 5-year SCD probability = 1 - 0.998^exp(Prognostic index).

Pearls and pitfalls

  • Not validated for age <16 years, prior SCD survivors, or infiltrative/metabolic phenocopies of HCM.
  • ESC guideline bands: <4% low, 4 to <6% intermediate, >=6% high 5-year risk.

References

  1. O'Mahony C, Jichi F, Pavlou M, et al. Eur Heart J. 2014;35(30):2010-20.