The Cardiovascular
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Glucose infusion rate (GIR)

Rate of intravenous dextrose delivery, normalized to body weight.

Glucose infusion rate (GIR)
Dextrose concentration
% (g/100 mL)
Infusion rate
mL/hr
Weight
Complete the fields above to see the result.

When to use

  • Calculating and titrating the rate of intravenous dextrose delivery in parenteral nutrition or neonatal glucose support.

Formula

GIR (mg/kg/min) = [dextrose concentration (%) x infusion rate (mL/hr) x 10] / [weight (kg) x 60].

Pearls and pitfalls

  • Typical maintenance GIR in neonates/infants is roughly 4-8 mg/kg/min; tolerance varies with gestational age and clinical status.
  • Recalculate whenever the infusion rate, dextrose concentration, or weight changes.

References

  1. Mirtallo J, Canada T, Johnson D, et al. Safe practices for parenteral nutrition. JPEN J Parenter Enteral Nutr. 2004;28(6):S39-70.