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Glasgow Prognostic Score (GPS) for cancer outcomes
Prognostic score in cancer based on CRP and albumin, reflecting the systemic inflammatory response.
Glasgow Prognostic Score (GPS) for cancer outcomes
C-reactive protein
mg/L
Albumin
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When to use
- Prognostic stratification in solid-organ cancers (originally validated in inoperable non-small-cell lung cancer) using two routine blood tests.
Formula
GPS = 0 if CRP <=10 mg/L and albumin >=3.5 g/dL; 1 if either CRP >10 mg/L or albumin <3.5 g/dL; 2 if both CRP >10 mg/L and albumin <3.5 g/dL.
Pearls and pitfalls
- The modified GPS (mGPS) scores 0 for CRP <=10 mg/L regardless of albumin - the two versions differ in patients with isolated hypoalbuminemia.