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GAP index for idiopathic pulmonary fibrosis mortality
Mortality staging in IPF from gender, age, physiology.
GAP index for idiopathic pulmonary fibrosis mortality
Sex
Age
FVC (% predicted)
DLCO (% predicted)
Result0 points (Stage I)
GAP stage I: approximately 5.6 % 1-year and 16.3 % 3-year mortality.
- GAP score (0-8)
- 0
- 1-year mortality
- 5.6 %
- 3-year mortality
- 16.3 %
When to use
- Estimating mortality risk and staging severity in idiopathic pulmonary fibrosis.
Formula
Points: Gender (male 1), Age (<=60 = 0, 61-65 = 1, >65 = 2), FVC%pred (>75 = 0, 50-75 = 1, <50 = 2), DLCO%pred (>55 = 0, 36-55 = 1, <=35 = 2, cannot perform = 3). Stage I 0-3, II 4-5, III 6-8.
Pearls and pitfalls
- Higher stage predicts higher 1-, 2-, and 3-year mortality and can inform transplant referral timing.