ToolsCalculators
Corrected Count Increment (CCI) for Platelet Transfusion
Adjusts platelet increment for body size and dose transfused.
Corrected Count Increment (CCI) for Platelet Transfusion
Pre-transfusion platelet count
/µL
Post-transfusion platelet count
/µL
Body surface area
m²
Platelets transfused
×10¹¹
Post-transfusion sample timing
Complete the fields above to see the result.
When to use
- Distinguishing immune (alloimmune) from non-immune (consumptive) causes of a poor platelet transfusion response.
Formula
CCI = (post-transfusion count − pre-transfusion count [/µL]) × body surface area (m²) / number of platelets transfused (×10¹¹).
Pearls and pitfalls
- A CCI ≥7500 at 1 hour or ≥4500 at 24 hours is generally considered an adequate response.
- Two consecutive inadequate CCIs on ABO-matched fresh platelets define refractoriness and warrant HLA antibody testing.