The Cardiovascular
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eGFR — CKD-EPI 2021 (creatinine)

Estimated glomerular filtration rate using the race-free 2021 CKD-EPI creatinine equation.

eGFR — CKD-EPI 2021 (creatinine)
Age
years
Sex
Serum creatinine
Complete the fields above to see the result.

When to use

  • Staging and monitoring chronic kidney disease. The 2021 equation removes the race coefficient used in earlier versions.

Formula

eGFR = 142 × min(Scr/κ, 1)^α × max(Scr/κ, 1)^−1.200 × 0.9938^age × 1.012 (if female), where κ = 0.7 (female) or 0.9 (male) and α = −0.241 (female) or −0.302 (male); Scr in mg/dL.

Pearls and pitfalls

  • Reported per 1.73 m² of body surface area; for drug dosing in patients of unusual size, de-index by multiplying by actual BSA/1.73.

References

  1. Inker LA, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021;385(19):1737–49.