ToolsCalculators
ATLAS score for Clostridioides difficile infection
Bedside score predicting response to therapy for C. difficile infection.
ATLAS score for Clostridioides difficile infection
Age
years
Concurrent treatment with systemic antibiotics (for another infection) during CDI therapy
Total leukocyte count
x10^9/L (K/uL)
Serum albumin
Serum creatinine
Complete the fields above to see the result.
When to use
- Stratifying patients with C. difficile infection at diagnosis to predict likelihood of clinical cure and help select therapy.
Formula
Sum of 5 items, each 0-2 points except antibiotics (0 or 2): Age (<60=0, 60-79=1, >=80=2), concurrent systemic Antibiotics (no=0, yes=2), Leukocyte count (<16=0, 16-25=1, >25 x10^9/L=2), Albumin (>35=0, 26-35=1, <=25 g/L=2), Serum creatinine (<=120=0, 121-179=1, >=180 umol/L=2). Range 0-10.
Pearls and pitfalls
- Derived and validated on two large fidaxomicin-vs-vancomycin trial databases; very ill patients (e.g. fulminant colitis, ICU) were under-represented.
- Not a severity score in itself, but a predictor of response to standard antibiotic therapy.