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ATLAS score for Clostridioides difficile infection
ATLAS score for Clostridioides difficile infection
Age
years
Concurrent treatment with systemic antibiotics (for another infection) during CDI therapy
Total leukocyte count
x10^9/L (K/uL)
Serum albumin
Serum creatinine
Complete the fields above to see the result.
When to use
- Stratifying patients with C. difficile infection at diagnosis to predict likelihood of clinical cure and help select therapy.
Formula
Sum of 5 items, each 0-2 points except antibiotics (0 or 2): Age (<60=0, 60-79=1, >=80=2), concurrent systemic Antibiotics (no=0, yes=2), Leukocyte count (<16=0, 16-25=1, >25 x10^9/L=2), Albumin (>35=0, 26-35=1, <=25 g/L=2), Serum creatinine (<=120=0, 121-179=1, >=180 umol/L=2). Range 0-10.
Pearls and pitfalls
- Derived and validated on two large fidaxomicin-vs-vancomycin trial databases; very ill patients (e.g. fulminant colitis, ICU) were under-represented.
- Not a severity score in itself, but a predictor of response to standard antibiotic therapy.